Diseases & Conditions > Disease > Metabolism > Anaerobic Metabolism

Anaerobic Metabolism

Anaerobic metabolism is the process by which the body produces energy from carbohydrates in the absence of oxygen.  It is a form of cellular respiration, and is sometimes instead referred to as anaerobic respiration.  The process is most common in prokaryotic organisms, such as bacteria, and is generally only used in humans and other animals when aerobic metabolism is unable to convert sufficient fuel into energy due to a lack of oxygen.  This occurs mainly during short periods of very intense exercise, such as during sprinting or in lifting weights, or manual work, and sometimes during extremely long periods of intense exercise.  Like it aerobic counterpart, anaerobic metabolism goes through the same standard cellular respiratory process of glycolysis, citric acid cycle (Krebs cycle), and electron transport chain.  It is similar, but not identical to cellular fermentation.  In fermentation, only the first part of the respiratory process is completed correctly; both anaerobic metabolism and cellular fermentation both occur mainly in the absence of oxygen.  Due to the lack of oxygen, anaerobic metabolism must be completed using another substance which has the same electronegative properties of oxygen (meaning that it combines very easily with positively charged proteins, such as hydrogen and carbon).  In prokaryotic organisms, these substances are inorganic molecules such as sulfates, nitrates, or pure sulfer.  In human beings the substance used is called phosphocreatine.  Phosphocreatine is used with glucose as it goes through the complete cellular respiration.  Due to role of phosphocreatine, however, the final role in anaerobic metabolism is not water and carbon dioxide, as it is in aerobic respiration, but lactic acid.  Lactic acid is secreted by the cells as a waste product, where it becomes infused into the blood stream and carried throughout the system to the muscles.  The lactic acid quickly builds up on the muscles, which is what causes muscle fatigue.  Anaerobic metabolism is not as efficient as aerobic respiration for this reason, and should not be endured for as long a period as its aerobic counterpart.  Nevertheless, anaerobic metabolism is an important part of a balanced exercise regime, as it helps build muscle strength and improves the efficiency of how the body burns calories.  This can greatly improve the body's basal metabolic rate, and can aid in the ability to burn unnessary fat and prevent its accumulation in the first place.   Many athletes have what they call the anaerobic threshold, which is the point where the know their body begins to employ anaerobic metabolism.  Cellular fermentation occurs when pyruvate which is produced by glycolysis is not sent into the mitochondrian for the next stage of cellular respiration, due to a lack of oxygen.  The pyruvate instead remains in the cytoplasm, where it is often converted into waste and excreted from the cell.  When this occurs it oxides the pyruvate, making it suceptible to reabsorption in other cells for use in cellular respiration.  Despite representing an incomplete from of cellular respiration, fermentation does provide some energy production, having produced ATP energy molecules during the initial glycolysis.  It is only a small percent of what is ultimately produced by full respiration, and for that reason the process is more common in prokaryotic bacteria cells.  In humans, it is considered fairly unhealthy, and leads to the creation of additional wastes, like lactic acid, without the benefits of full energy production.

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